Structure Activity Relationship Study of benzo[d]thiazol-2(3H)one Based Receptor Ligands

Herein we report the SAR study which involved structural modifications to the linker length, aryl substitution and alkylamine ring size of the benzo[d]thiazol-2(3H)one based sigma receptor ( ) ligands. Many compounds in this series displayed low nanomolar affinity for the receptor subtypes. In parti...

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Main Authors: Bhat, Rohit, Fishback, James A., Matsumoto, Rae R., Poupaert, Jacques H., McCurdy, Christopher R.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762478/
https://ncbi.nlm.nih.gov/pubmed/23867168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.06.032
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