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Sigma-2 Receptors Play a Role in Cellular Metabolism: Stimulation of Glycolytic Hallmarks by CM764 in Human SK-N-SH Neuroblastoma

Sigma-2 receptors are attractive antineoplastic targets due to their ability to induce apoptosis and their upregulation in rapidly proliferating cancer cells compared with healthy tissue. However, this role is inconsistent with overexpression in cancer, which is typically associated with upregulatio...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Nicholson, Hilary, Mesangeau, Christophe, McCurdy, Christopher R., Bowen, Wayne D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746495/
https://ncbi.nlm.nih.gov/pubmed/26574517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.228387
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