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Determination of a highly selective mixed-affinity sigma receptor ligand, in rat plasma by ultra performance liquid chromatography mass spectrometry and its application to a pharmacokinetic study
A selective, rapid and sensitive ultra performance liquid chromatography mass spectrometry (UPLC/MS) method was developed and validated to quantitate a highly selective mixed-affinity sigma receptor ligand, CM156 (3-(4-(4-cyclohexylpiperazin-1-yl)butyl)benzo[d] thiazole-2(3H)-thione), in rat plasma....
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Główni autorzy: | , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
2011
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992999/ https://ncbi.nlm.nih.gov/pubmed/22406103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2011.12.013 |
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