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6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site

Histone acetyltransferases are important enzymes that regulate various cellular functions, such as epigenetic control of DNA transcription. Development of HAT inhibitors with high selectivity and potency will provide powerful mechanistic tools for the elucidation of the biological functions of HATs...

詳細記述

保存先:
書誌詳細
主要な著者: Ghizzoni, Massimo, Wu, Jiang, Gao, Tielong, Haisma, Hidde J., Dekker, Frank J., Zheng, Y. George
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399519/
https://ncbi.nlm.nih.gov/pubmed/22100137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.11.001
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