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Functional copper at the acetyl-CoA synthase active site

The bifunctional CO dehydrogenase/acetyl-CoA synthase (CODH/ACS) plays a central role in the Wood–Ljungdahl pathway of autotrophic CO(2) fixation. A recent structure of the Moorella thermoacetica enzyme revealed that the ACS active site contains a [4Fe-4S] cluster bridged to a binuclear Cu-Ni site....

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Detalhes bibliográficos
Main Authors: Seravalli, Javier, Gu, Weiwei, Tam, Annie, Strauss, Erick, Begley, Tadhg P., Cramer, Stephen P., Ragsdale, Stephen W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152983/
https://ncbi.nlm.nih.gov/pubmed/12589021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0436720100
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