Selection of Cyclic-Peptide Inhibitors Targeting Aurora Kinase A: Problems and Solutions

Por Shomin, Carolyn D., Restituyo, Elizabeth, Cox, Kurt J., Ghosh, Indraneel
Publicado em 2011

Testing the Promiscuity of Commercial Kinase Inhibitors Against the AGC Kinase Group Using a Split-luciferase Screen

Por Jester, Benjamin W., Gaj, Alicia, Shomin, Carolyn D., Cox, Kurt J., Ghosh, Indraneel
Publicado em 2012

Use of Ionically Tagged Glycosyl Donors in the Synthesis of Oligosaccharide Libraries

Por Kim, Eun Ju, Gray, Gary R.
Publicado em 2009

Simultaneous determination of methylcarbamate and ethylcarbamate in fermented foods and beverages by derivatization and GC-MS analysis

Por Shin, Ho-Sang, Yang, Eun-Young
Publicado em 2012

Structure Activity Relationships of 1,4-Dihydropyridines That Act as Enhancers of the Vanilloid Receptor 1 (TRPV1)

Por Roh, Eun Joo, Keller, Jason M., Olah, Zoltan, Iadarola, Michael J., Jacobson, Kenneth A.
Publicado em 2008

Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines

Por Parhi, Ajit K., Zhang, Yongzheng, Saionz, Kurt W., Pradhan, Padmanava, Kaul, Malvika, Trivedi, Kalkal, Pilch, Daniel S., LaVoie, Edmond J.
Publicado em 2013

Hepatitis C Virus NS3/4A Protease Inhibitors Incorporating Flexible P2 Quinoxalines Target Drug Resistant Viral Variants

Por Matthew, Ashley N., Zephyr, Jacqueto, Hill, Caitlin. J., Jahangir, Muhammad, Newton, Alicia, Petropoulos, Christos J., Huang, Wei, Kurt-Yilmaz, Nese, Schiffer, Celia A., Ali, Akbar
Publicado no J Med Chem (2017)

Edible Myrciaria vexator fruits: Bioactive phenolics for potential COPD therapy

Por Dastmalchi, Keyvan, Flores, Gema, Wu, Shi-Biao, Ma, Chunhui, Dabo, Abdoulaye J., Whalen, Kathleen, Reynertson, Kurt A., Foronjy, Robert F., D́Armiento, Jeanine M., Kennelly, Edward J.
Publicado no Bioorg Med Chem (2012)

Quinoxaline-Based Linear HCV NS3/4A Protease Inhibitors Exhibit Potent Activity against Drug Resistant Variants

Por Rusere, Linah N., Matthew, Ashley N., Lockbaum, Gordon J., Jahangir, Muhammad, Newton, Alicia, Petropoulos, Christos J., Huang, Wei, Kurt Yilmaz, Nese, Schiffer, Celia A., Ali, Akbar
Publicado no ACS Med Chem Lett (2018)

Microtubule-Stabilizing Agents as Potential Therapeutics for Neurodegenerative Disease

Por Brunden, Kurt R., Trojanowski, John Q., Smith, Amos B., Lee, Virginia M.-Y., Ballatore, Carlo
Publicado em 2013

Synthesis and antioxidant properties of dendritic polyphenols

Por Lee, Choon Young, Sharma, Ajit, Cheong, Jae Eun, Nelson, Julie L.
Publicado em 2009

(S)-4-Trimethylsilyl-3-butyn-2-ol as an auxiliary for stereocontrolled synthesis of salinosporamide analogs with modifications at positions C2 and C5

Por Blasdel, Landy K., Lee, DongEun, Sun, Binyuan, Myers, Andrew G.
Publicado em 2013

Non-proteinogenic amino acids in the pThr-2 position of a pentamer peptide that confer high binding affinity for the polo box domain (PBD) of polo-like kinase 1 (Plk1)

Por Qian, Wen-Jian, Park, Jung-Eun, Lee, Kyung S., Burke, Terrence R.
Publicado em 2012

Targeting efflux pumps to overcome antifungal drug resistance

Por Holmes, Ann R, Cardno, Tony S, Strouse, J Jacob, Ivnitski-Steele, Irena, Keniya, Mikhail V, Lackovic, Kurt, Monk, Brian C, Sklar, Larry A, Cannon, Richard D
Publicado no Future Med Chem (2016)

MT-Stabilizer, Dictyostatin, Exhibits Prolonged Brain Retention and Activity: Potential Therapeutic Implications

Por Brunden, Kurt R., Gardner, Nicola M., James, Michael J., Yao, Yuemang, Trojanowski, John Q., Lee, Virginia M.-Y., Paterson, Ian, Ballatore, Carlo, Smith, Amos B.
Publicado em 2013

Corrigendum to “Synthesis and cytotoxic activity of novel Aring cleaved ursolic acid derivatives in human nonsmall cell lung cancer cells” [Eur. J. Med. Chem. 123 (2016) 317–331]

Por Mendes, Vanessa I. S., Bartholomeusz, Geoffrey A., Ayres, Mary, Gandhi, Varsha, Salvador, Jorge A. R.
Publicado no Eur J Med Chem (2016)

Structure Property Relationships of Carboxylic Acid Isosteres

Por Lassalas, Pierrik, Gay, Bryant, Lasfargeas, Caroline, James, Michael J., Tran, Van, Vijayendran, Krishna G., Brunden, Kurt R., Kozlowski, Marisa C., Thomas, Craig J., Smith, Amos B., Huryn, Donna M., Ballatore, Carlo
Publicado no J Med Chem (2016)

Discovery of Brain-Penetrant, Orally Bioavailable Aminothienopyridazine Inhibitors of Tau Aggregation

Por Ballatore, Carlo, Brunden, Kurt R., Piscitelli, Francesco, James, Michael J., Crowe, Alex, Yao, Yuemang, Hyde, Edward, Trojanowski, John Q., Lee, Virginia M.-Y., Smith, Amos B.
Publicado em 2010

Effects on Polo-like Kinase 1 Polo-box Domain Binding Affinities of Peptides Incurred by Structural Variation at the Phosphoamino Acid Position

Por Qian, Wenjian, Park, Jung-Eun, Liu, Fa, Lee, Kyung S., Burke, Terrence R.
Publicado em 2012

SAR refinement of antileishmanial N(2),N(4)-disubstituted quinazoline-2,4-diamines

Por Zhu, Xiaohua, Van Horn, Kurt S., Barber, Megan, Yang, Sihyung, Wang, Michael Zhuo, Manetsch, Roman, Werbovetz, Karl A.
Publicado no Bioorg Med Chem (2015)