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SAR refinement of antileishmanial N(2),N(4)-disubstituted quinazoline-2,4-diamines

Visceral leishmaniasis is a neglected parasitic disease that has a high fatality rate in the absence of treatment. New drugs that are inexpensive, orally active, and effective could be useful tools in the fight against this disease. We previously showed that N(2),N(4)-disubstituted quinazoline-2,4-d...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Zhu, Xiaohua, Van Horn, Kurt S., Barber, Megan, Yang, Sihyung, Wang, Michael Zhuo, Manetsch, Roman, Werbovetz, Karl A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536136/
https://ncbi.nlm.nih.gov/pubmed/25749014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.02.020
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