SAR refinement of antileishmanial N(2),N(4)-disubstituted quinazoline-2,4-diamines

Visceral leishmaniasis is a neglected parasitic disease that has a high fatality rate in the absence of treatment. New drugs that are inexpensive, orally active, and effective could be useful tools in the fight against this disease. We previously showed that N(2),N(4)-disubstituted quinazoline-2,4-d...

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Publicado en:Bioorg Med Chem
Autores principales: Zhu, Xiaohua, Van Horn, Kurt S., Barber, Megan, Yang, Sihyung, Wang, Michael Zhuo, Manetsch, Roman, Werbovetz, Karl A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536136/
https://ncbi.nlm.nih.gov/pubmed/25749014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.02.020
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