Elucidation of Vasodilation Response and Structure Activity Relationships of N(2),N(4)-Disubstituted Quinazoline 2,4-Diamines in a Rat Pulmonary Artery Model

Pulmonary arterial hypertension (PAH) is a rare and progressive disease arising from various etiologies and pathogenesis. PAH decreases life expectancy due to pulmonary vascular remodeling, elevation of mean pulmonary arterial pressure, and ultimately progresses to heart failure. While clinical trea...

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Foilsithe in:Molecules
Main Authors: Paracha, Tamkeen Urooj, Pobsuk, Nattakarn, Salaloy, Nattapas, Suphakun, Praphasri, Pekthong, Dumrongsak, Hannongbua, Supa, Choowongkomon, Kiattawee, Khorana, Nantaka, Temkitthawon, Prapapan, Ingkaninan, Kornkanok, Gleeson, M. Paul, Chootip, Krongkarn
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2019
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358775/
https://ncbi.nlm.nih.gov/pubmed/30646523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24020281
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