Elucidation of Vasodilation Response and Structure Activity Relationships of N(2),N(4)-Disubstituted Quinazoline 2,4-Diamines in a Rat Pulmonary Artery Model

Pulmonary arterial hypertension (PAH) is a rare and progressive disease arising from various etiologies and pathogenesis. PAH decreases life expectancy due to pulmonary vascular remodeling, elevation of mean pulmonary arterial pressure, and ultimately progresses to heart failure. While clinical trea...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Paracha, Tamkeen Urooj, Pobsuk, Nattakarn, Salaloy, Nattapas, Suphakun, Praphasri, Pekthong, Dumrongsak, Hannongbua, Supa, Choowongkomon, Kiattawee, Khorana, Nantaka, Temkitthawon, Prapapan, Ingkaninan, Kornkanok, Gleeson, M. Paul, Chootip, Krongkarn
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358775/
https://ncbi.nlm.nih.gov/pubmed/30646523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24020281
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires