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Characterizing the Antimicrobial Activity of N(2),N(4)-Disubstituted Quinazoline-2,4-Diamines toward Multidrug-Resistant Acinetobacter baumannii

We previously reported a series of N(2),N(4)-disubstituted quinazoline-2,4-diamines as dihydrofolate reductase inhibitors with potent in vitro and in vivo antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) strains. In this work, we extended our previous study to the Gr...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Fleeman, Renee, Van Horn, Kurt S., Barber, Megan M., Burda, Whittney N., Flanigan, David L., Manetsch, Roman, Shaw, Lindsey N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444175/
https://ncbi.nlm.nih.gov/pubmed/28289036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00059-17
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