A carregar...
SAR study on N(2),N(4)-disubstituted pyrimidine-2,4-diamines as effective CDK2/CDK9 inhibitors and antiproliferative agents
Cyclin-dependent kinases (CDKs) are pivotal kinases in cell cycle transition and gene transcription. A series of N(2),N(4)-diphenylpyrimidine-2,4-diamines were previously identified as potent CDK2/CDK9 inhibitors. To explore the SAR of this structural prototype, twenty-four novel N(2),N(4)-disubstit...
Na minha lista:
| Publicado no: | RSC Adv |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society of Chemistry
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5890689/ https://ncbi.nlm.nih.gov/pubmed/29682280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ra01440j |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|