SAR refinement of antileishmanial N(2),N(4)-disubstituted quinazoline-2,4-diamines

Visceral leishmaniasis is a neglected parasitic disease that has a high fatality rate in the absence of treatment. New drugs that are inexpensive, orally active, and effective could be useful tools in the fight against this disease. We previously showed that N(2),N(4)-disubstituted quinazoline-2,4-d...

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Vydáno v:Bioorg Med Chem
Hlavní autoři: Zhu, Xiaohua, Van Horn, Kurt S., Barber, Megan, Yang, Sihyung, Wang, Michael Zhuo, Manetsch, Roman, Werbovetz, Karl A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536136/
https://ncbi.nlm.nih.gov/pubmed/25749014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.02.020
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