Targeting efflux pumps to overcome antifungal drug resistance

Resistance to antifungal drugs is an increasingly significant clinical problem. The most common antifungal resistance encountered is efflux pump-mediated resistance of Candida species to azole drugs. One approach to overcome this resistance is to inhibit the pumps and chemosensitize resistant strain...

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Foilsithe in:Future Med Chem
Main Authors: Holmes, Ann R, Cardno, Tony S, Strouse, J Jacob, Ivnitski-Steele, Irena, Keniya, Mikhail V, Lackovic, Kurt, Monk, Brian C, Sklar, Larry A, Cannon, Richard D
Formáid: Artigo
Teanga:Inglês
Foilsithe: Future Science Ltd 2016
Ábhair:
Review
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827819/
https://ncbi.nlm.nih.gov/pubmed/27463566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2016-0050
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