β(2)-Adrenergic Receptor Lysosomal Trafficking Is Regulated by Ubiquitination of Lysyl Residues in Two Distinct Receptor Domains

Por Xiao, Kunhong, Shenoy, Sudha K.
Publicado em 2011

A tale of two sites: How ubiquitination of a G protein-coupled receptor is coupled to its lysosomal trafficking from distinct receptor domains

Por Sarker, Subhodeep, Xiao, Kunhong, Shenoy, Sudha K
Publicado em 2011

Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling

Por Shukla, Arun K., Xiao, Kunhong, Lefkowitz, Robert J.
Publicado em 2011

Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass spectrometry (CDSiL-MS)

Por Kahsai, Alem W., Rajagopal, Sudarshan, Sun, Jinpeng, Xiao, Kunhong
Publicado no Nat Protoc (2014)

Studying the regulation of endosomal cAMP production in GPCR signaling

Por Gidon, Alexandre, Feinstein, Timothy N., Xiao, Kunhong, Vilardaga, Jean-Pierre
Publicado no Methods Cell Biol (2015)

Inferring the Sign of Kinase-Substrate Interactions by Combining Quantitative Phosphoproteomics with a Literature-Based Mammalian Kinome Network

Por Hernandez, Marylens, Lachmann, Alexander, Zhao, Shan, Xiao, Kunhong, Ma'ayan, Avi
Publicado em 2010

Overexpression of TNNI3K, a cardiac specific MAPKKK, promotes cardiac dysfunction

Por Tang, Hao, Xiao, Kunhong, Mao, Lan, Rockman, Howard A., Marchuk, Douglas A.
Publicado em 2012

Recent developments in biased agonism

Por Wisler, James W., Xiao, Kunhong, Thomsen, Alex R.B., Lefkowitz, Robert J.
Publicado em 2013

Nedd4 Mediates Agonist-dependent Ubiquitination, Lysosomal Targeting, and Degradation of the β(2)-Adrenergic Receptor

Por Shenoy, Sudha K., Xiao, Kunhong, Venkataramanan, Vidya, Snyder, Peter M., Freedman, Neil J., Weissman, Allan M.
Publicado em 2008

Arresting a Transient Receptor Potential (TRP) Channel: β-ARRESTIN 1 MEDIATES UBIQUITINATION AND FUNCTIONAL DOWN-REGULATION OF TRPV4

Por Shukla, Arun K., Kim, Jihee, Ahn, Seungkirl, Xiao, Kunhong, Shenoy, Sudha K., Liedtke, Wolfgang, Lefkowitz, Robert J.
Publicado em 2010

β(2)-adrenergic receptor control of endosomal PTH receptor signaling via Gβγ

Por Jean-Alphonse, Frédéric G, Wehbi, Vanessa L, Chen, Jingming, Noda, Masaki, Taboas, Juan M, Xiao, Kunhong, Vilardaga, Jean-Pierre
Publicado no Nat Chem Biol (2016)

Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent ERK signaling

Por Liu, Hongda, Zhang, Qun, Li, Kangshuai, Gong, Zheng, Liu, Zhaochen, Xu, Yunfei, Swaney, Mary Hannah, Xiao, Kunhong, Chen, Yuxin
Publicado no Oncotarget (2016)

UBIQUITINATION OF β-ARRESTIN LINKS 7-TRANSMEMBRANE RECEPTOR ENDOCYTOSIS AND ERK ACTIVATION

Por Shenoy, Sudha K., Barak, Larry S., Xiao, Kunhong, Ahn, Seungkirl, Berthouze, Magali, Shukla, Arun K., Luttrell, Louis M., Lefkowitz, Robert J.
Publicado em 2007

Multiple ligand-specific conformations of the β(2)-adrenergic receptor

Por Kahsai, Alem W, Xiao, Kunhong, Rajagopal, Sudarshan, Ahn, Seungkirl, Shukla, Arun K, Sun, Jinpeng, Oas, Terrence G, Lefkowitz, Robert J
Publicado em 2011

The Posterior Cricoarytenoid Muscle Is Spared from MuRF1-Mediated Muscle Atrophy in Mice with Acute Lung Injury

Por Files, D. Clark, Xiao, Kunhong, Zhang, Tan, Liu, Chun, Qian, Jiang, Zhao, Weiling, Morris, Peter E., Delbono, Osvaldo, Feng, Xin
Publicado em 2014

Origins of PDZ Binding Specificity. A Computational and Experimental Study Using NHERF1 and the Parathyroid Hormone Receptor

Por Mamonova, Tatyana, Zhang, Qiangmin, Chandra, Mintu, Collins, Brett M., Sarfo, Edward, Bu, Zimei, Xiao, Kunhong, Bisello, Alessandro, Friedman, Peter A.
Publicado no Biochemistry (2017)

β-arrestin mediated localization of Smoothened to the primary cilium

Por Kovacs, Jeffrey J., Whalen, Erin J., Liu, Renshui, Xiao, Kunhong, Kim, Jihee, Chen, Minyong, Wang, Jiangbo, Chen, Wei, Lefkowitz, Robert J.
Publicado em 2008

Oxygen-Regulated β(2)-Adrenergic Receptor Hydroxylation by EGLN3 and Ubiquitylation by pVHL

Por Xie, Liang, Xiao, Kunhong, Whalen, Erin J., Forrester, Michael T., Freeman, Robert S., Fong, Guohua, Gygi, Steven P., Lefkowitz, Robert J., Stamler, Jonathan S.
Publicado em 2009

MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors

Por Han, Sang-oh, Xiao, Kunhong, Kim, Jihee, Wu, Jiao-Hui, Wisler, James W., Nakamura, Nobuhiro, Freedman, Neil J., Shenoy, Sudha K.
Publicado em 2012

Functional Human α7 Nicotinic Acetylcholine Receptor (nAChR) Generated from Escherichia coli

Por Tillman, Tommy S., Alvarez, Frances J. D., Reinert, Nathan J., Liu, Chuang, Wang, Dawei, Xu, Yan, Xiao, Kunhong, Zhang, Peijun, Tang, Pei
Publicado no J Biol Chem (2016)