Multiple ligand-specific conformations of the β(2)-adrenergic receptor

Seven-transmembrane receptors (7TMRs), also called G protein–coupled receptors (GPCRs), represent the largest class of drug targets, and they can signal through several distinct mechanisms including those mediated by G proteins and the multifunctional adaptor proteins β-arrestins. Moreover, several...

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Bibliografiska uppgifter
Huvudupphovsmän: Kahsai, Alem W, Xiao, Kunhong, Rajagopal, Sudarshan, Ahn, Seungkirl, Shukla, Arun K, Sun, Jinpeng, Oas, Terrence G, Lefkowitz, Robert J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404607/
https://ncbi.nlm.nih.gov/pubmed/21857662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.634
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