Functional Human α7 Nicotinic Acetylcholine Receptor (nAChR) Generated from Escherichia coli

Human Cys-loop receptors are important therapeutic targets. High-resolution structures are essential for rational drug design, but only a few are available due to difficulties in obtaining sufficient quantities of protein suitable for structural studies. Although expression of proteins in E. coli of...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Tillman, Tommy S., Alvarez, Frances J. D., Reinert, Nathan J., Liu, Chuang, Wang, Dawei, Xu, Yan, Xiao, Kunhong, Zhang, Peijun, Tang, Pei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000075/
https://ncbi.nlm.nih.gov/pubmed/27385587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.729970
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