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A tale of two sites: How ubiquitination of a G protein-coupled receptor is coupled to its lysosomal trafficking from distinct receptor domains

The β(2)-adrenergic receptor (β(2)AR) is a prototypical G(s)-coupled receptor belonging to the superfamily of seven transmembrane spanning heptahelical receptors (7TMRs or G protein-coupled receptors [GPCRs])—therapeutically the most diverse and accessible class of cell surface receptors. The classi...

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Bibliografske podrobnosti
Main Authors: Sarker, Subhodeep, Xiao, Kunhong, Shenoy, Sudha K
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204120/
https://ncbi.nlm.nih.gov/pubmed/22046454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.4.5.16458
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