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Role of ubiquitination in endocytic trafficking of G protein-coupled receptors

Lysyl-ubiquitination has long been known to target cytoplasmic proteins for proteasomal degradation, and there is now extensive evidence that ubiquitination functions in vacuolar/lysosomal targeting of membrane proteins from both the biosynthetic and endocytic pathways. G protein-coupled receptors (...

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Detalhes bibliográficos
Main Authors: Hislop, James N, von Zastrow, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625703/
https://ncbi.nlm.nih.gov/pubmed/20854416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2010.01121.x
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