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Dysbindin Promotes the Post-Endocytic Sorting of G Protein-Coupled Receptors to Lysosomes
BACKGROUND: Dysbindin, a cytoplasmic protein long known to function in the biogenesis of specialized lysosome-related organelles (LROs), has been reported to reduce surface expression of D2 dopamine receptors in neurons. Dysbindin is broadly expressed, and dopamine receptors are members of the large...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824829/ https://ncbi.nlm.nih.gov/pubmed/20174469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009325 |
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