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Alternative Splicing Determines the Post-endocytic Sorting Fate of G-protein-coupled Receptors
Mu-type opioid receptors are physiologically important G-protein-coupled receptors that are generally thought to recycle after agonist-induced endocytosis. Here we show that several alternatively spliced receptor variants fail to do so efficiently because of splice-mediated removal of an endocytic s...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2602910/ https://ncbi.nlm.nih.gov/pubmed/18936093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806588200 |
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