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Alternative Splicing Determines the Post-endocytic Sorting Fate of G-protein-coupled Receptors

Mu-type opioid receptors are physiologically important G-protein-coupled receptors that are generally thought to recycle after agonist-induced endocytosis. Here we show that several alternatively spliced receptor variants fail to do so efficiently because of splice-mediated removal of an endocytic s...

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Bibliografiska uppgifter
Huvudupphovsmän: Tanowitz, Michael, Hislop, James N., von Zastrow, Mark
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602910/
https://ncbi.nlm.nih.gov/pubmed/18936093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806588200
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