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Dysbindin Promotes the Post-Endocytic Sorting of G Protein-Coupled Receptors to Lysosomes

BACKGROUND: Dysbindin, a cytoplasmic protein long known to function in the biogenesis of specialized lysosome-related organelles (LROs), has been reported to reduce surface expression of D2 dopamine receptors in neurons. Dysbindin is broadly expressed, and dopamine receptors are members of the large...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Marley, Aaron, von Zastrow, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824829/
https://ncbi.nlm.nih.gov/pubmed/20174469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009325
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