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Overexpression of TNNI3K, a cardiac specific MAPKKK, promotes cardiac dysfunction

Cardiac Troponin I-interacting kinase (TNNI3K) is a cardiac specific kinase whose biological function remains largely unknown. We have recently shown that TNNI3K expression greatly accelerates cardiac dysfunction in mouse models of cardiomyopathy, indicating an important role in modulating disease p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tang, Hao, Xiao, Kunhong, Mao, Lan, Rockman, Howard A., Marchuk, Douglas A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535516/
https://ncbi.nlm.nih.gov/pubmed/23085512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.10.004
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