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Tnni3k Modifies Disease Progression in Murine Models of Cardiomyopathy

The Calsequestrin (Csq) transgenic mouse model of cardiomyopathy exhibits wide variation in phenotypic progression dependent on genetic background. Seven heart failure modifier (Hrtfm) loci modify disease progression and outcome. Here we report Tnni3k (cardiac Troponin I-interacting kinase) as the g...

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Detalhes bibliográficos
Main Authors: Wheeler, Ferrin C., Tang, Hao, Marks, Odessa A., Hadnott, Tracy N., Chu, Pei-Lun, Mao, Lan, Rockman, Howard A., Marchuk, Douglas A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731170/
https://ncbi.nlm.nih.gov/pubmed/19763165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000647
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