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Dissection of a Quantitative Trait Locus for PR Interval Duration Identifies Tnni3k as a Novel Modulator of Cardiac Conduction

Atrio-ventricular conduction disease is a common feature in Mendelian rhythm disorders associated with sudden cardiac death and is characterized by prolongation of the PR interval on the surface electrocardiogram (ECG). Prolongation of the PR interval is also a strong predictor of atrial fibrillatio...

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Detalhes bibliográficos
Main Authors: Lodder, Elisabeth M., Scicluna, Brendon P., Milano, Annalisa, Sun, Albert Y., Tang, Hao, Remme, Carol Ann, Moerland, Perry D., Tanck, Michael W. T., Pitt, Geoffrey S., Marchuk, Douglas A., Bezzina, Connie R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516546/
https://ncbi.nlm.nih.gov/pubmed/23236294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003113
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