Human Papillomavirus Type 16 E7 Maintains Elevated Levels of the cdc25A Tyrosine Phosphatase during Deregulation of Cell Cycle Arrest

Por Nguyen, Don X., Westbrook, Thomas F., McCance, Dennis J.
Publicado em 2002

E7 Abolishes Raf-Induced Arrest via Mislocalization of p21(Cip1)

Por Westbrook, Thomas F., Nguyen, Don X., Thrash, Barry R., McCance, Dennis J.
Publicado em 2002

Plk2 regulates mitotic spindle orientation and mammary gland development

Por Villegas, Elizabeth, Kabotyanski, Elena B., Shore, Amy N., Creighton, Chad J., Westbrook, Thomas F., Rosen, Jeffrey M.
Publicado em 2014

A role for PVRL4-driven cell–cell interactions in tumorigenesis

Por Pavlova, Natalya N, Pallasch, Christian, Elia, Andrew EH, Braun, Christian J, Westbrook, Thomas F, Hemann, Michael, Elledge, Stephen J
Publicado em 2013

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

Por Luo, Ji, Emanuele, Michael J., Li, Danan, Creighton, Chad J., Schlabach, Michael R., Westbrook, Thomas F., Wong, Kwok-kin, Elledge, Stephen J.
Publicado em 2009

Control of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasis

Por Cheung, William K.C., Zhao, Minghui, Liu, Zongzhi, Stevens, Laura E., Cao, Paul D., Fang, Justin E., Westbrook, Thomas F., Nguyen, Don X.
Publicado em 2013

A systematic analysis of factors localized to damaged chromatin reveals PARP-dependent recruitment of transcription factors

Por Izhar, Lior, Adamson, Britt, Ciccia, Alberto, Lewis, Jedd, Pontano-Vaites, Laura, Leng, Yumei, Liang, Anthony C., Westbrook, Thomas F., Harper, J. Wade, Elledge, Stephen J.
Publicado no Cell Rep (2015)

SCF(βTRCP)Controls Oncogenic Transformation and Neural Differentiation Through REST Degradation

Por Westbrook, Thomas F., Hu, Guang, Ang, Xiaolu L., Mulligan, Peter, Pavlova, Natalya N., Liang, Anthony, Leng, Yumei, Maehr, Rene, Shi, Yang, Harper, J. Wade, Elledge, Stephen J.
Publicado em 2008

Selective Small Molecule Stat3 Inhibitor Reduces Breast Cancer Tumor-Initiating Cells and Improves Recurrence Free Survival in a Human-Xenograft Model

Por Dave, Bhuvanesh, Landis, Melissa D., Dobrolecki, Lacey E., Wu, Meng-Fen, Zhang, Xiaomei, Westbrook, Thomas F., Hilsenbeck, Susan G., Liu, Dan, Lewis, Michael T., Tweardy, David J., Chang, Jenny C.
Publicado em 2012

Correction: Selective Small Molecule Stat3 Inhibitor Reduces Breast Cancer Tumor-Initiating Cells and Improves Recurrence Free Survival in a Human-Xenograft Model

Por Dave, Bhuvanesh, Landis, Melissa D., Dobrolecki, Lacey E., Wu, Meng-Fen, Zhang, Xiaomei, Westbrook, Thomas F., Hilsenbeck, Susan G., Liu, Dan, Lewis, Michael T., Tweardy, David J., Chang, Jenny C.
Publicado em 2012

Tcf3 promotes cell migration and wound repair through regulation of lipocalin 2

Por Miao, Qi, Ku, Amy T., Nishino, Yudai, Howard, Jeffrey M., Rao, Ajay S., Shaver, Timothy M., Garcia, Gloria E., Le, Diep N., Karlin, Kristen L., Westbrook, Thomas F., Poli, Valeria, Nguyen, Hoang
Publicado em 2014

The Osteogenic Niche Promotes Early-Stage Bone Colonization of Disseminated Breast Cancer Cells

Por Wang, Hai, Yu, Cuijuan, Gao, Xia, Welte, Thomas, Muscarella, Aaron M., Tian, Lin, Zhao, Hong, Zhao, Zhen, Du, Shiyu, Tao, Jianning, Lee, Brendan, Westbrook, Thomas F., Wong, Stephen T. C., Jin, Xin, Rosen, Jeffrey M., Osborne, C. Kent, Zhang, Xiang H.-F.
Publicado no Cancer Cell (2015)

Cancer Proliferation Gene Discovery Through Functional Genomics

Por Schlabach, Michael R., Luo, Ji, Solimini, Nicole L., Hu, Guang, Xu, Qikai, Li, Mamie Z., Zhao, Zhenming, Smogorzewska, Agata, Sowa, Mathew E., Ang, Xiaolu L., Westbrook, Thomas F., Liang, Anthony C., Chang, Kenneth, Hackett, Jennifer A., Harper, J. Wade, Hannon, Gregory J., Elledge, Stephen J.
Publicado em 2008

TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau

Por Rousseaux, Maxime WC, de Haro, Maria, Lasagna-Reeves, Cristian A, De Maio, Antonia, Park, Jeehye, Jafar-Nejad, Paymaan, Al-Ramahi, Ismael, Sharma, Ajay, See, Lauren, Lu, Nan, Vilanova-Velez, Luis, Klisch, Tiemo J, Westbrook, Thomas F, Troncoso, Juan C, Botas, Juan, Zoghbi, Huda Y
Publicado no eLife (2016)

The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo

Por Meerbrey, Kristen L., Hu, Guang, Kessler, Jessica D., Roarty, Kevin, Li, Mamie Z., Fang, Justin E., Herschkowitz, Jason I., Burrows, Anna E., Ciccia, Alberto, Sun, Tingting, Schmitt, Earlene M., Bernardi, Ronald J., Fu, Xiaoyong, Bland, Christopher S., Cooper, Thomas A., Schiff, Rachel, Rosen, Jeffrey M., Westbrook, Thomas F., Elledge, Stephen J.
Publicado em 2011

Genetic screens reveal RAS/MAPK/MSK1 modulate ataxin 1 protein levels and toxicity in SCA1

Por Park, Jeehye, Al-Ramahi, Ismael, Tan, Qiumin, Mollema, Nissa, Diaz-Garcia, Javier R., Gallego-Flores, Tatiana, Lu, Hsiang-Chih, Lagalwar, Sarita, Duvick, Lisa, Kang, Hyojin, Lee, Yoontae, Jafar-Nejad, Paymaan, Sayegh, Layal S., Richman, Ronald, Liu, Xiuyun, Gao, Yan, Shaw, Chad A., Arthur, J. Simon C., Orr, Harry T., Westbrook, Thomas F., Botas, Juan, Zoghbi, Huda Y.
Publicado em 2013

AN ANIMAL MODEL OF MYC-DRIVEN MEDULLOBLASTOMA

Por Pei, Yanxin, Moore, Colin E., Wang, Jun, Tewari, Alok K., Eroshkin, Alexey, Cho, Yoon-Jae, Witt, Hendrik, Korshunov, Andrey, Read, Tracy-Ann, Sun, Julia L., Schmitt, Earlene M., Miller, C. Ryan, Buckley, Anne F., McLendon, Roger E., Westbrook, Thomas F., Northcott, Paul A., Taylor, Michael D., Pfister, Stefan M., Febbo, Phillip G., Wechsler-Reya, Robert J.
Publicado em 2012

Oncogenic mTOR signaling recruits myeloid-derived suppressor cells to promote tumor initiation

Por Welte, Thomas, Kim, Ik Sun, Tian, Lin, Gao, Xia, Wang, Hai, Li, June, Holdman, Xue B., Herschkowitz, Jason I., Pond, Adam, Xie, Guorui, Kurley, Sarah, Nguyen, Tuan, Liao, Lan, Dobrolecki, Lacey E., Mo, Qianxing, Edwards, Dean P., Huang, Shixia, Xin, Li, Xu, Jianming, Li, Yi, Lewis, Michael T., Wang, Tian, Westbrook, Thomas F., Rosen, Jeffrey M., Zhang, Xiang H.-F.
Publicado no Nat Cell Biol (2016)

The oncogenic STP axis promotes triple-negative breast cancer via degradation of the REST tumor suppressor

Por Karlin, Kristen L., Mondal, Gourish, Hartman, Jessica K., Tyagi, Siddhartha, Kurley, Sarah J., Bland, Chris S., Hsu, Tiffany Y.T., Renwick, Alexander, Fang, Justin E., Migliaccio, Ilenia, Callaway, Celetta, Nair, Amritha, Dominguez-Vidana, Rocio, Nguyen, Don X., Osborne, C. Kent, Schiff, Rachel, Yu-Lee, Li-Yuan, Jung, Sung Y., Edwards, Dean P., Hilsenbeck, Susan G., Rosen, Jeffrey M., Zhang, Xiang, Shaw, Chad A., Couch, Fergus J., Westbrook, Thomas F.
Publicado no Cell Rep (2014)

A sumoylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis

Por Kessler, Jessica D., Kahle, Kristopher T., Sun, Tingting, Meerbrey, Kristen L., Schlabach, Michael R., Schmitt, Earlene M., Skinner, Samuel O., Xu, Qikai, Li, Mamie Z., Hartman, Zachary C., Rao, Mitchell, Yu, Peng, Dominguez-Vidana, Rocio, Liang, Anthony C., Solimini, Nicole L., Bernardi, Ronald J., Yu, Bing, Hsu, Tiffany, Golding, Ido, Luo, Ji, Osborne, C. Kent, Creighton, Chad J., Hilsenbeck, Susan G., Schiff, Rachel, Shaw, Chad A., Elledge, Stephen J., Westbrook, Thomas F.
Publicado em 2011