A systematic analysis of factors localized to damaged chromatin reveals PARP-dependent recruitment of transcription factors

Localization to sites of DNA damage is a hallmark of DNA damage response (DDR) proteins. To identify new DDR factors, we screened epitope-tagged proteins for localization to sites of chromatin damaged by UV laser microirradiation and found >120 proteins that localize to damaged chromatin. These i...

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Publicado no:Cell Rep
Main Authors: Izhar, Lior, Adamson, Britt, Ciccia, Alberto, Lewis, Jedd, Pontano-Vaites, Laura, Leng, Yumei, Liang, Anthony C., Westbrook, Thomas F., Harper, J. Wade, Elledge, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464939/
https://ncbi.nlm.nih.gov/pubmed/26004182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.04.053
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