A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

Many proteins that respond to DNA damage are recruited to DNA lesions. We used a proteomics approach that coupled isotopic labeling with chromatin fractionation and mass spectrometry to uncover proteins that associate with damaged DNA, many of which are involved in DNA repair or nucleolar function....

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Xehetasun bibliografikoak
Egile Nagusiak: Chou, Danny M., Adamson, Britt, Dephoure, Noah E., Tan, Xu, Nottke, Amanda C., Hurov, Kristen E., Gygi, Steven P., Colaiácovo, Monica P., Elledge, Stephen J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2010
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972950/
https://ncbi.nlm.nih.gov/pubmed/20937877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012946107
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