NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression

Pluripotent cells possess the ability to differentiate into any cell type. Commitment to differentiate into specific lineages requires strict control of gene expression to coordinate the downregulation of lineage inappropriate genes while enabling the expression of lineage-specific genes. The nucleo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Reynolds, Nicola, Salmon-Divon, Mali, Dvinge, Heidi, Hynes-Allen, Antony, Balasooriya, Gayan, Leaford, Donna, Behrens, Axel, Bertone, Paul, Hendrich, Brian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273378/
https://ncbi.nlm.nih.gov/pubmed/22139358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.431
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