MBD2/NuRD and MBD3/NuRD, Two Distinct Complexes with Different Biochemical and Functional Properties

The human genome contains a number of methyl CpG binding proteins that translate DNA methylation into a physiological response. To gain insight into the function of MBD2 and MBD3, we first applied protein tagging and mass spectrometry. We show that MBD2 and MBD3 assemble into mutually exclusive dist...

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Bibliographic Details
Main Authors: Le Guezennec, Xavier, Vermeulen, Michiel, Brinkman, Arie B., Hoeijmakers, Wieteke A. M., Cohen, Adrian, Lasonder, Edwin, Stunnenberg, Hendrik G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1347035/
https://ncbi.nlm.nih.gov/pubmed/16428440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.3.843-851.2006
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