MBD2/NuRD and MBD3/NuRD, Two Distinct Complexes with Different Biochemical and Functional Properties

The human genome contains a number of methyl CpG binding proteins that translate DNA methylation into a physiological response. To gain insight into the function of MBD2 and MBD3, we first applied protein tagging and mass spectrometry. We show that MBD2 and MBD3 assemble into mutually exclusive dist...

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Detalhes bibliográficos
Main Authors: Le Guezennec, Xavier, Vermeulen, Michiel, Brinkman, Arie B., Hoeijmakers, Wieteke A. M., Cohen, Adrian, Lasonder, Edwin, Stunnenberg, Hendrik G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1347035/
https://ncbi.nlm.nih.gov/pubmed/16428440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.3.843-851.2006
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