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Sall4 controls differentiation of pluripotent cells independently of the Nucleosome Remodelling and Deacetylation (NuRD) complex

Sall4 is an essential transcription factor for early mammalian development and is frequently overexpressed in cancer. Although it is reported to play an important role in embryonic stem cell (ESC) self-renewal, whether it is an essential pluripotency factor has been disputed. Here, we show that Sall...

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Détails bibliographiques
Publié dans:Development
Auteurs principaux: Miller, Anzy, Ralser, Meryem, Kloet, Susan L., Loos, Remco, Nishinakamura, Ryuichi, Bertone, Paul, Vermeulen, Michiel, Hendrich, Brian
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047675/
https://ncbi.nlm.nih.gov/pubmed/27471257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.139113
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