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Plk2 regulates mitotic spindle orientation and mammary gland development

Disruptions in polarity and mitotic spindle orientation contribute to the progression and evolution of tumorigenesis. However, little is known about the molecular mechanisms regulating these processes in vivo. Here, we demonstrate that Polo-like kinase 2 (Plk2) regulates mitotic spindle orientation...

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Bibliografske podrobnosti
Main Authors: Villegas, Elizabeth, Kabotyanski, Elena B., Shore, Amy N., Creighton, Chad J., Westbrook, Thomas F., Rosen, Jeffrey M.
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957376/
https://ncbi.nlm.nih.gov/pubmed/24598160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.108258
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