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Plk2 regulates mitotic spindle orientation and mammary gland development

Disruptions in polarity and mitotic spindle orientation contribute to the progression and evolution of tumorigenesis. However, little is known about the molecular mechanisms regulating these processes in vivo. Here, we demonstrate that Polo-like kinase 2 (Plk2) regulates mitotic spindle orientation...

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Autors principals: Villegas, Elizabeth, Kabotyanski, Elena B., Shore, Amy N., Creighton, Chad J., Westbrook, Thomas F., Rosen, Jeffrey M.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957376/
https://ncbi.nlm.nih.gov/pubmed/24598160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.108258
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