The mechanism of Golgi segregation during mitosis is cell type-specific

Por Stanley, Harold, Botas, Juan, Malhotra, Vivek
Publicado em 1997

The level of DLDB/CHIP controls the activity of the LIM homeodomain protein Apterous: evidence for a functional tetramer complex in vivo

Por Rincón-Limas, Diego E., Lu, Cheng-Hsin, Canal, Inmaculada, Botas, Juan
Publicado em 2000

Drosophila Mitf regulates the V-ATPase and the lysosomal-autophagic pathway

Por Bouché, Valentina, Espinosa, Alma Perez, Leone, Luigi, Sardiello, Marco, Ballabio, Andrea, Botas, Juan
Publicado no Autophagy (2016)

Genetic Modifiers of MeCP2 Function in Drosophila

Por Cukier, Holly N., Perez, Alma M., Collins, Ann L., Zhou, Zhaolan, Zoghbi, Huda Y., Botas, Juan
Publicado em 2008

Smaug/SAMD4A Restores Translational Activity of CUGBP1 and Suppresses CUG-Induced Myopathy

Por de Haro, Maria, Al-Ramahi, Ismael, Jones, Karlie R., Holth, Jerrah K., Timchenko, Lubov T., Botas, Juan
Publicado em 2013

Neurotoxic protein expression reveals connections between the circadian clock and mating behavior in Drosophila

Por Kadener, Sebastian, Villella, Adriana, Kula, Elzbieta, Palm, Kristyna, Pyza, Elzbieta, Botas, Juan, Hall, Jeffrey C., Rosbash, Michael
Publicado em 2006

Genetic suppression of neurodegeneration and neurotransmitter release abnormalities caused by expanded full-length huntingtin accumulating in the cytoplasm.

Por Romero, Eliana, Cha, Guang-Ho, Verstreken, Patrik, Ly, Cindy V., Hughes, Robert, Bellen, Hugo J., Botas, Juan
Publicado em 2008

The Drosophila FMRP and LARK RNA-Binding Proteins Function Together to Regulate Eye Development and Circadian Behavior

Por Sofola, Oyinkan, Sundram, Vasudha, Ng, Fanny, Kleyner, Yelena, Morales, Joannella, Botas, Juan, Jackson, F. Rob, Nelson, David L.
Publicado em 2008

RNA binding proteins hnRNP A2/B1 and CUGBP1 suppress Fragile X CGG premutation repeat-induced neurodegeneration in a Drosophila model of FXTAS

Por Sofola, Oyinkan A., Jin, Peng, Qin, Yunlong, Duan, Ranhui, Liu, Huijie, de Haro, Maria, Nelson, David L., Botas, Juan
Publicado em 2007

Conservation of the expression and function of apterous orthologs in Drosophila and mammals

Por Rincón-Limas, Diego E., Lu, Cheng-Hsin, Canal, Inmaculada, Calleja, Manuel, Rodríguez-Esteban, Concepción, Izpisúa-Belmonte, Juan Carlos, Botas, Juan
Publicado em 1999

TORC1 Inhibition by Rapamycin Promotes Antioxidant Defences in a Drosophila Model of Friedreich’s Ataxia

Por Calap-Quintana, Pablo, Soriano, Sirena, Llorens, José Vicente, Al-Ramahi, Ismael, Botas, Juan, Moltó, María Dolores, Martínez-Sebastián, María José
Publicado no PLoS One (2015)

Inhibition of Lipid Signaling Enzyme Diacylglycerol Kinase ϵ Attenuates Mutant Huntingtin Toxicity

Por Zhang, Ningzhe, Li, Bensheng, Al-Ramahi, Ismael, Cong, Xin, Held, Jason M., Kim, Eugene, Botas, Juan, Gibson, Bradford W., Ellerby, Lisa M.
Publicado em 2012

Metal Homeostasis Regulators Suppress FRDA Phenotypes in a Drosophila Model of the Disease

Por Soriano, Sirena, Calap-Quintana, Pablo, Llorens, José Vicente, Al-Ramahi, Ismael, Gutiérrez, Lucía, Martínez-Sebastián, María José, Botas, Juan, Moltó, María Dolores
Publicado no PLoS One (2016)

Tau Loss Attenuates Neuronal Network Hyperexcitability in Mouse and Drosophila Genetic Models of Epilepsy

Por Holth, Jerrah K., Bomben, Valerie C., Reed, J. Graham, Inoue, Taeko, Younkin, Linda, Younkin, Steven G., Pautler, Robia G., Botas, Juan, Noebels, Jeffrey L.
Publicado em 2013

PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in spinocerebellar ataxia type 1

Por Bondar, Vitaliy V, Adamski, Carolyn J, Onur, Tarik S, Tan, Qiumin, Wang, Li, Diaz-Garcia, Javier, Park, Jeehye, Orr, Harry T, Botas, Juan, Zoghbi, Huda Y
Publicado no Hum Mol Genet (2018)

dAtaxin-2 Mediates Expanded Ataxin-1-Induced Neurodegeneration in a Drosophila Model of SCA1

Por Al-Ramahi, Ismael, Pérez, Alma M, Lim, Janghoo, Zhang, Minghang, Sorensen, Rie, de Haro, Maria, Branco, Joana, Pulst, Stefan M, Zoghbi, Huda Y, Botas, Juan
Publicado em 2007

A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity

Por Yao, Yuwei, Cui, Xiaotian, Al-Ramahi, Ismael, Sun, Xiaoli, Li, Bo, Hou, Jiapeng, Difiglia, Marian, Palacino, James, Wu, Zhi-Ying, Ma, Lixiang, Botas, Juan, Lu, Boxun
Publicado no eLife (2015)

Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain

Por Shirasaki, Dyna I., Greiner, Erin R., Al-Ramahi, Ismael, Gray, Michelle, Boontheung, Pinmanee, Geschwind, Daniel H., Botas, Juan, Coppola, Giovanni, Horvath, Steve, Loo, Joseph A., Yang, X. William
Publicado em 2012

Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease

Por Chouhan, Amit K., Guo, Caiwei, Hsieh, Yi-Chen, Ye, Hui, Senturk, Mumine, Zuo, Zhongyuan, Li, Yarong, Chatterjee, Shreyasi, Botas, Juan, Jackson, George R., Bellen, Hugo J., Shulman, Joshua M.
Publicado no Acta Neuropathol Commun (2016)

Matrix Metalloproteinases are Modifiers of Huntingtin Proteolysis and Toxicity in Huntington’s Disease

Por Miller, John P., Holcomb, Jennifer, Al-Ramahi, Ismael, de Haro, Maria, Gafni, Juliette, Zhang, Ningzhe, Kim, Eugene, Sanhueza, Mario, Torcassi, Cameron, Kwak, Seung, Botas, Juan, Hughes, Robert E., Ellerby, Lisa M.
Publicado em 2010