Matrix Metalloproteinases are Modifiers of Huntingtin Proteolysis and Toxicity in Huntington’s Disease

Proteolytic cleavage of huntingtin (Htt) is known to be a key event in the pathogenesis of Huntington’s disease (HD). Our understanding of proteolytic processing of Htt has thus far focused on the cysteine protease families of caspases and calpains. Identifying critical protease families involved in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Miller, John P., Holcomb, Jennifer, Al-Ramahi, Ismael, de Haro, Maria, Gafni, Juliette, Zhang, Ningzhe, Kim, Eugene, Sanhueza, Mario, Torcassi, Cameron, Kwak, Seung, Botas, Juan, Hughes, Robert E., Ellerby, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098887/
https://ncbi.nlm.nih.gov/pubmed/20670829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.06.021
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados