Metal Homeostasis Regulators Suppress FRDA Phenotypes in a Drosophila Model of the Disease

Friedreich’s ataxia (FRDA), the most commonly inherited ataxia in populations of European origin, is a neurodegenerative disorder caused by a decrease in frataxin levels. One of the hallmarks of the disease is the accumulation of iron in several tissues including the brain, and frataxin has been pro...

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Опубликовано в: :PLoS One
Главные авторы: Soriano, Sirena, Calap-Quintana, Pablo, Llorens, José Vicente, Al-Ramahi, Ismael, Gutiérrez, Lucía, Martínez-Sebastián, María José, Botas, Juan, Moltó, María Dolores
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951068/
https://ncbi.nlm.nih.gov/pubmed/27433942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159209
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