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Metal Homeostasis Regulators Suppress FRDA Phenotypes in a Drosophila Model of the Disease
Friedreich’s ataxia (FRDA), the most commonly inherited ataxia in populations of European origin, is a neurodegenerative disorder caused by a decrease in frataxin levels. One of the hallmarks of the disease is the accumulation of iron in several tissues including the brain, and frataxin has been pro...
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Publicado no: | PLoS One |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4951068/ https://ncbi.nlm.nih.gov/pubmed/27433942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159209 |
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