Overexpression of Human and Fly Frataxins in Drosophila Provokes Deleterious Effects at Biochemical, Physiological and Developmental Levels

BACKGROUND: Friedreich's ataxia (FA), the most frequent form of inherited ataxias in the Caucasian population, is caused by a reduced expression of frataxin, a highly conserved protein. Model organisms have contributed greatly in the efforts to decipher the function of frataxin; however, the pr...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Navarro, Juan A., Llorens, José V., Soriano, Sirena, Botella, José A., Schneuwly, Stephan, Martínez-Sebastián, María J., Moltó, María D.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136927/
https://ncbi.nlm.nih.gov/pubmed/21779322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021017
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы