Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease

Common neurodegenerative proteinopathies, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), are characterized by the misfolding and aggregation of toxic protein species, including the amyloid beta (Aß) peptide, microtubule-associated protein Tau (Tau), and alpha-synuclein (αSyn) protein...

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Enregistré dans:
Détails bibliographiques
Publié dans:Acta Neuropathol Commun
Auteurs principaux: Chouhan, Amit K., Guo, Caiwei, Hsieh, Yi-Chen, Ye, Hui, Senturk, Mumine, Zuo, Zhongyuan, Li, Yarong, Chatterjee, Shreyasi, Botas, Juan, Jackson, George R., Bellen, Hugo J., Shulman, Joshua M.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918017/
https://ncbi.nlm.nih.gov/pubmed/27338814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0333-4
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