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Loss of proteins associated with amyotrophic lateral sclerosis affects lysosomal acidification via different routes
Abnormal accumulation of proteins is a hallmark of a variety of neurological diseases including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Maintenance of protein homeostasis (proteostasis) in neurons via proteasomal and macroautophagy/autophagy-lysosomal degradation is th...
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| Publicado no: | Autophagy |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6613899/ https://ncbi.nlm.nih.gov/pubmed/31032688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1609863 |
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