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Angiogenin Loss-of-Function Mutations in Amyotrophic Lateral Sclerosis
OBJECTIVE: Heterozygous missense mutations in the coding region of angiogenin (ANG), an angiogenic ribonuclease, have been reported in amyotrophic lateral sclerosis (ALS) patients. However, the role of ANG in motor neuron physiology and the functional consequences of these mutations are unknown. We...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2776820/ https://ncbi.nlm.nih.gov/pubmed/17886298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21221 |
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