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Targeting angiogenin in therapy of amyotropic lateral sclerosis
BACKGROUND: Missense heterozygous mutations in the coding region of angiogenin (ANG) gene, encoding a 14 kDa angiogenic RNase, were recently found in patients of amyotropic lateral sclerosis (ALS). Functional analyses have shown that these are loss-of-function mutations, implying that angiogenin def...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782700/ https://ncbi.nlm.nih.gov/pubmed/18781822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.12.10.1229 |
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