The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo

The discovery of RNAi has revolutionized loss-of-function genetic studies in mammalian systems. However, significant challenges still remain to fully exploit RNAi for mammalian genetics. For instance, genetic screens and in vivo studies could be broadly improved by methods that allow inducible and u...

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Detalhes bibliográficos
Main Authors: Meerbrey, Kristen L., Hu, Guang, Kessler, Jessica D., Roarty, Kevin, Li, Mamie Z., Fang, Justin E., Herschkowitz, Jason I., Burrows, Anna E., Ciccia, Alberto, Sun, Tingting, Schmitt, Earlene M., Bernardi, Ronald J., Fu, Xiaoyong, Bland, Christopher S., Cooper, Thomas A., Schiff, Rachel, Rosen, Jeffrey M., Westbrook, Thomas F., Elledge, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048138/
https://ncbi.nlm.nih.gov/pubmed/21307310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019736108
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