The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo

The discovery of RNAi has revolutionized loss-of-function genetic studies in mammalian systems. However, significant challenges still remain to fully exploit RNAi for mammalian genetics. For instance, genetic screens and in vivo studies could be broadly improved by methods that allow inducible and u...

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Bibliografiske detaljer
Main Authors: Meerbrey, Kristen L., Hu, Guang, Kessler, Jessica D., Roarty, Kevin, Li, Mamie Z., Fang, Justin E., Herschkowitz, Jason I., Burrows, Anna E., Ciccia, Alberto, Sun, Tingting, Schmitt, Earlene M., Bernardi, Ronald J., Fu, Xiaoyong, Bland, Christopher S., Cooper, Thomas A., Schiff, Rachel, Rosen, Jeffrey M., Westbrook, Thomas F., Elledge, Stephen J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048138/
https://ncbi.nlm.nih.gov/pubmed/21307310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019736108
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