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Human Papillomavirus Type 16 E7 Maintains Elevated Levels of the cdc25A Tyrosine Phosphatase during Deregulation of Cell Cycle Arrest
Essential to the oncogenic properties of human papillomavirus type 16 (HPV-16) are the activities encoded by the early gene product E7. HPV-16 E7 (E7.16) binds to cellular factors involved in cell cycle regulation and differentiation. These include the retinoblastoma tumor suppressor protein (Rb) an...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2002
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136809/ https://ncbi.nlm.nih.gov/pubmed/11752153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.2.619-632.2002 |
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