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Human Papillomavirus Type 16 E7 Maintains Elevated Levels of the cdc25A Tyrosine Phosphatase during Deregulation of Cell Cycle Arrest

Essential to the oncogenic properties of human papillomavirus type 16 (HPV-16) are the activities encoded by the early gene product E7. HPV-16 E7 (E7.16) binds to cellular factors involved in cell cycle regulation and differentiation. These include the retinoblastoma tumor suppressor protein (Rb) an...

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Detalhes bibliográficos
Main Authors: Nguyen, Don X., Westbrook, Thomas F., McCance, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136809/
https://ncbi.nlm.nih.gov/pubmed/11752153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.2.619-632.2002
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