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E7 Abolishes Raf-Induced Arrest via Mislocalization of p21(Cip1)

The cellular response to oncogenic Ras depends upon the presence or absence of cooperating mutations. In the absence of immortalizing oncogenes or genetic lesions, activation of the Ras/Raf pathway results in a p21(Cip1)-dependent cellular arrest. The human papillomavirus oncoprotein E7 transforms p...

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書目詳細資料
Main Authors: Westbrook, Thomas F., Nguyen, Don X., Thrash, Barry R., McCance, Dennis J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC139800/
https://ncbi.nlm.nih.gov/pubmed/12242284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.20.7041-7052.2002
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