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E7 Abolishes Raf-Induced Arrest via Mislocalization of p21(Cip1)

The cellular response to oncogenic Ras depends upon the presence or absence of cooperating mutations. In the absence of immortalizing oncogenes or genetic lesions, activation of the Ras/Raf pathway results in a p21(Cip1)-dependent cellular arrest. The human papillomavirus oncoprotein E7 transforms p...

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Détails bibliographiques
Auteurs principaux: Westbrook, Thomas F., Nguyen, Don X., Thrash, Barry R., McCance, Dennis J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC139800/
https://ncbi.nlm.nih.gov/pubmed/12242284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.20.7041-7052.2002
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