E7 Abolishes Raf-Induced Arrest via Mislocalization of p21(Cip1)

The cellular response to oncogenic Ras depends upon the presence or absence of cooperating mutations. In the absence of immortalizing oncogenes or genetic lesions, activation of the Ras/Raf pathway results in a p21(Cip1)-dependent cellular arrest. The human papillomavirus oncoprotein E7 transforms p...

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Detalles Bibliográficos
Main Authors: Westbrook, Thomas F., Nguyen, Don X., Thrash, Barry R., McCance, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Transcriptional Regulation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC139800/
https://ncbi.nlm.nih.gov/pubmed/12242284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.20.7041-7052.2002
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