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E7 Abolishes Raf-Induced Arrest via Mislocalization of p21(Cip1)

The cellular response to oncogenic Ras depends upon the presence or absence of cooperating mutations. In the absence of immortalizing oncogenes or genetic lesions, activation of the Ras/Raf pathway results in a p21(Cip1)-dependent cellular arrest. The human papillomavirus oncoprotein E7 transforms p...

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Bibliografske podrobnosti
Main Authors: Westbrook, Thomas F., Nguyen, Don X., Thrash, Barry R., McCance, Dennis J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC139800/
https://ncbi.nlm.nih.gov/pubmed/12242284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.20.7041-7052.2002
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