From breaking bad to worse: exploiting homologous DNA repair deficiency in cancer

Por Hemann, Michael T.
Publicado no Cancer Discov (2014)

NEK4 STATUS INFLUENCES DIFFERENTIAL SENSITIVITY TO MICROTUBULE POISONS

Por Doles, Jason, Hemann, Michael T.
Publicado em 2010

Wild-derived inbred mouse strains have short telomeres

Por Hemann, Michael T., Greider, Carol W.
Publicado em 2000

DNA damage-mediated induction of a chemoresistant niche

Por Gilbert, Luke A, Hemann, Michael T
Publicado em 2010

Chemotherapeutic Resistance: Surviving Stressful Situations

Por Gilbert, Luke A., Hemann, Michael T.
Publicado em 2011

Context-specific roles for paracrine IL-6 in lymphomagenesis

Por Gilbert, Luke A., Hemann, Michael T.
Publicado em 2012

The Chromatin Regulator CHD8 Is a Context-Dependent Mediator of Cell Survival in Murine Hematopoietic Malignancies

Por Shingleton, Jennifer R., Hemann, Michael T.
Publicado no PLoS One (2015)

Disrupting the Pairing Between let-7 and Hmga2 Enhances Oncogenic Transformation

Por Mayr, Christine, Hemann, Michael T., Bartel, David P.
Publicado em 2007

Intratumor heterogeneity alters most effective drugs in designed combinations

Por Zhao, Boyang, Hemann, Michael T., Lauffenburger, Douglas A.
Publicado em 2014

Reply to Azuaje: Predicting effective combined therapies for heterogeneous tumors

Por Zhao, Boyang, Hemann, Michael T., Lauffenburger, Douglas A.
Publicado em 2014

Modeling Tumor Clonal Evolution for Drug Combinations Design

Por Zhao, Boyang, Hemann, Michael T., Lauffenburger, Douglas A.
Publicado no Trends Cancer (2016)

Understanding Resistance to Combination Chemotherapy

Por Pritchard, Justin R., Lauffenburger, Douglas A., Hemann, Michael T.
Publicado em 2012

A senescence secretory switch mediated by PI3K/AKT/mTOR activation controls chemoprotective endothelial secretory responses

Por Bent, Eric H., Gilbert, Luke A., Hemann, Michael T.
Publicado no Genes Dev (2016)

Error-prone translesion synthesis mediates acquired chemoresistance

Por Xie, Kun, Doles, Jason, Hemann, Michael T., Walker, Graham C.
Publicado em 2010

Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy?

Por Yamanaka, Kinrin, Chatterjee, Nimrat, Hemann, Michael T., Walker, Graham C.
Publicado no PLoS Genet (2017)

Exploiting synthetic lethal interactions for targeted cancer therapy

Por Reinhardt, H. Christian, Jiang, Hai, Hemann, Michael T., Yaffe, Michael B.
Publicado em 2009

Integrated Network Analyses for Functional Genomic Studies in Cancer

Por Wilson, Jennifer L., Hemann, Michael T., Fraenkel, Ernest, Lauffenburger, Douglas A.
Publicado em 2013

Addressing genetic tumor heterogeneity through computationally predictive combination therapy

Por Zhao, Boyang, Pritchard, Justin R., Lauffenburger, Douglas A., Hemann, Michael T.
Publicado em 2013

Integrated regulatory models for inference of subtype‐specific susceptibilities in glioblastoma

Por Liu, Yunpeng, Shi, Ning, Regev, Aviv, He, Shan, Hemann, Michael T
Publicado no Mol Syst Biol (2020)

Predicting cancer drug mechanisms of action using molecular network signatures()

Por Pritchard, Justin R., Bruno, Peter M., Hemann, Michael T., Lauffenburger, Douglas A.
Publicado em 2013