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Modeling Tumor Clonal Evolution for Drug Combinations Design
Cancer is a clonal evolutionary process. This presents challenges for effective therapeutic intervention, given the constant selective pressure towards drug resistance. Mathematical modeling from population genetics, evolutionary dynamics, and engineering perspectives are being increasingly employed...
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| Publicado no: | Trends Cancer |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5400294/ https://ncbi.nlm.nih.gov/pubmed/28435907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2016.02.001 |
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