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Modeling Tumor Clonal Evolution for Drug Combinations Design
Cancer is a clonal evolutionary process. This presents challenges for effective therapeutic intervention, given the constant selective pressure towards drug resistance. Mathematical modeling from population genetics, evolutionary dynamics, and engineering perspectives are being increasingly employed...
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| 出版年: | Trends Cancer |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5400294/ https://ncbi.nlm.nih.gov/pubmed/28435907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2016.02.001 |
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