DNA damage-mediated induction of a chemoresistant niche

Por Gilbert, Luke A, Hemann, Michael T
Publicado em 2010

Chemotherapeutic Resistance: Surviving Stressful Situations

Por Gilbert, Luke A., Hemann, Michael T.
Publicado em 2011

Context-specific roles for paracrine IL-6 in lymphomagenesis

Por Gilbert, Luke A., Hemann, Michael T.
Publicado em 2012

The promise and challenge of in vivo delivery for genome therapeutics

Por Wilson, Ross C, Gilbert, Luke A
Publicado no ACS Chem Biol (2017)

A senescence secretory switch mediated by PI3K/AKT/mTOR activation controls chemoprotective endothelial secretory responses

Por Bent, Eric H., Gilbert, Luke A., Hemann, Michael T.
Publicado no Genes Dev (2016)

A protein tagging system for signal amplification in gene expression and fluorescence imaging

Por Tanenbaum, Marvin E., Gilbert, Luke A., Qi, Lei S., Weissman, Jonathan S., Vale, Ronald D.
Publicado no Cell (2014)

Toxoplasma gondii Targets a Protein Phosphatase 2C to the Nuclei of Infected Host Cells

Por Gilbert, Luke A., Ravindran, Sandeep, Turetzky, Jay M., Boothroyd, John C., Bradley, Peter J.
Publicado em 2007

CRISPR interference (CRISPRi) for sequence-specific control of gene expression

Por Larson, Matthew H, Gilbert, Luke A, Wang, Xiaowo, Lim, Wendell A, Weissman, Jonathan S, Qi, Lei S
Publicado em 2013

Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation

Por Braun, Christian J., Bruno, Peter M., Horlbeck, Max A., Gilbert, Luke A., Weissman, Jonathan S., Hemann, Michael T.
Publicado no Proc Natl Acad Sci U S A (2016)

Defining principles of combination drug mechanisms of action

Por Pritchard, Justin R., Bruno, Peter M., Gilbert, Luke A., Capron, Kelsey L., Lauffenburger, Douglas A., Hemann, Michael T.
Publicado em 2013

BCL-2 family genetic profiling reveals microenvironment-specific determinants of chemotherapeutic response

Por Pritchard, Justin R., Gilbert, Luke A., Meacham, Corbin E., Ricks, Jennifer L., Jiang, Hai, Lauffenburger, Douglas A., Hemann, Michael T.
Publicado em 2011

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

Por Qi, Lei S., Larson, Matthew H., Gilbert, Luke A., Doudna, Jennifer A., Weissman, Jonathan S., Arkin, Adam P., Lim, Wendell A.
Publicado em 2013

A Thioredoxin Family Protein of the Apicoplast Periphery Identifies Abundant Candidate Transport Vesicles in Toxoplasma gondii

Por DeRocher, Amy E., Coppens, Isabelle, Karnataki, Anuradha, Gilbert, Luke A., Rome, Michael E., Feagin, Jean E., Bradley, Peter J., Parsons, Marilyn
Publicado em 2008

Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity

Por Nguyen, Duy P., Miyaoka, Yuichiro, Gilbert, Luke A., Mayerl, Steven J., Lee, Brian H., Weissman, Jonathan S., Conklin, Bruce R., Wells, James A.
Publicado no Nat Commun (2016)

Nucleosomes impede Cas9 access to DNA in vivo and in vitro

Por Horlbeck, Max A, Witkowsky, Lea B, Guglielmi, Benjamin, Replogle, Joseph M, Gilbert, Luke A, Villalta, Jacqueline E, Torigoe, Sharon E, Tjian, Robert, Weissman, Jonathan S
Publicado no eLife (2016)

Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System

Por Chen, Baohui, Gilbert, Luke A., Cimini, Beth A., Schnitzbauer, Joerg, Zhang, Wei, Li, Gene-Wei, Park, Jason, Blackburn, Elizabeth H., Weissman, Jonathan S., Qi, Lei S., Huang, Bo
Publicado em 2013

Versatile protein tagging in cells with split fluorescent protein

Por Kamiyama, Daichi, Sekine, Sayaka, Barsi-Rhyne, Benjamin, Hu, Jeffrey, Chen, Baohui, Gilbert, Luke A., Ishikawa, Hiroaki, Leonetti, Manuel D., Marshall, Wallace F., Weissman, Jonathan S., Huang, Bo
Publicado no Nat Commun (2016)

Next-generation libraries for robust RNA interference-based genome-wide screens

Por Kampmann, Martin, Horlbeck, Max A., Chen, Yuwen, Tsai, Jordan C., Bassik, Michael C., Gilbert, Luke A., Villalta, Jacqueline E., Kwon, S. Chul, Chang, Hyeshik, Kim, V. Narry, Weissman, Jonathan S.
Publicado no Proc Natl Acad Sci U S A (2015)

Combinatorial genetics in liver repopulation and carcinogenesis with a novel in vivo CRISPR activation platform

Por Wangensteen, Kirk J., Wang, Yue J., Dou, Zhixun, Wang, Amber W., Mosleh-Shirazi, Elham, Horlbeck, Max A., Gilbert, Luke A., Weissman, Jonathan S., Berger, Shelley L., Kaestner, Klaus H.
Publicado no Hepatology (2018)

Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation

Por Horlbeck, Max A, Gilbert, Luke A, Villalta, Jacqueline E, Adamson, Britt, Pak, Ryan A, Chen, Yuwen, Fields, Alexander P, Park, Chong Yon, Corn, Jacob E, Kampmann, Martin, Weissman, Jonathan S
Publicado no eLife (2016)