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Error-prone translesion synthesis mediates acquired chemoresistance

The development of cancer drug resistance is a persistent clinical problem limiting the successful treatment of disseminated malignancies. However, the molecular mechanisms by which initially chemoresponsive tumors develop therapeutic resistance remain poorly understood. Error-prone translesional DN...

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Hlavní autoři: Xie, Kun, Doles, Jason, Hemann, Michael T., Walker, Graham C.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996453/
https://ncbi.nlm.nih.gov/pubmed/21068378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011412107
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