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Error-prone translesion synthesis mediates acquired chemoresistance
The development of cancer drug resistance is a persistent clinical problem limiting the successful treatment of disseminated malignancies. However, the molecular mechanisms by which initially chemoresponsive tumors develop therapeutic resistance remain poorly understood. Error-prone translesional DN...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996453/ https://ncbi.nlm.nih.gov/pubmed/21068378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011412107 |
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