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NEK4 STATUS INFLUENCES DIFFERENTIAL SENSITIVITY TO MICROTUBULE POISONS

While microtubule poisons are commonly used for the treatment of diverse malignancies, relatively little is known about cellular factors that determine the relative efficacy of these drugs. Here, we identified the NIMA kinase, Nek4, in a genetic screen for mediators of the response to the front-line...

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Detalhes bibliográficos
Main Authors: Doles, Jason, Hemann, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946156/
https://ncbi.nlm.nih.gov/pubmed/20103636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2113
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